| 시상하부를 침범한 다발성경화증 환자에서 발생한 증후성 기면증 |
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신원철, 김대성, 신동진 |
1가천의과대학교 신경과
2부산대학교 의과대학 신경과 |
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| Symptomatic Narcolepsy associated with Lesion of Hypothalamus in Multiple Sclerosis |
| Won Chul Shin, Dae-Sung Kim, Dong Jin Shin |
1Department of Neurology, Gachon Medical School
2Department of Neurology, Pusan National University School of Medicine* |
| Corresponding Author:
Won Chul Shin ,Tel: +82-32-460-3437, Fax: +82-32-460-3344, Email: shinwc@ghil.com |
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Received: December 5, 2004 Accepted: December 17, 2004 Published online: December 31, 2004 |
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| ABSTRACT |
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We report a rare case of multiple sclerosis(MS) with hypothalamic lesions. A 33-year-old man with long history of MS was admitted with
acute hypersomnia. He did not have sleep paralysis, hypnagogic hallucination, or cataplexy. Brain MRI showed a new plaque in both hypothalamus
and thalamus. Polysomnography revealed severe obstructive sleep apnea syndrome. On the multiple sleep latency test(MSLT), average
sleep latency was 54 seconds and there were noted 3 SOREM(Sleep Onset REM) on 5 trial. His sleepiness improved following treatment
with steroid and methylphenidate. 4 month later, follow-up polysomnography and MSLT were performed. There were no differences in API
during full night polysomnography but no SOREM in MSLT was observed. |
| Keywords:
narcolepsy | multiple sclerosis | polysomnography | multiple sleep latency test(MSLT) |
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