수면위상지연증후군에서 광치료의 효과 |
윤동주, 주은연, 한선정, 최수정, 홍승봉 |
성균관대학교 의과대학 신경과학교실 |
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Effects of light therapy on patients with delayed sleep phase syndrome |
Dong Joo Yun, Eun Yeon Joo, Sun Jung Han, Su Jung Choi, Seung Bong Hong |
Department of Neurology, Sleep Disorders Clinic, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea |
Corresponding Author:
Seung Bong Hong ,Tel: +82-2-3410-3592, Fax: +82-2-3410-0052, Email: sbhong@smc.samsung.co.kr |
Received: June 5, 2005 Accepted: June 14, 2005 Published online: June 30, 2005 |
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ABSTRACT |
Background : Light therapy (LT) is a potent tool for the treatment of circadian rhythm sleep disorder. We present the method and treatment effect of LT in patients with delayed sleep phase syndrome (DSPS).
Methods : We enrolled 11 patients (M:F=4:7). Eleven of them had DSPS. Two of them who had post-encephalitic epilepsy were dropped out because they showed photosensitive seizures to LT. Thus the remaining 9 patients received LT with a bright light box for consecutive 7-10 days. The patients sit in front of a “light box”, which emits 10,000 lux of full spectrum fluorescent light for the periods of 30-45 minutes daily in the morning right after wake-up. Light was restricted by reducing room light for 1hour before light-off at bedtime. The timing of LT was readjusted everyday to the scheduled wake-up time of each day.
Results : By the LT, the average bedtime was advanced from 02:30 a.m. (range; 01:30-5:50 a.m.) to 23:15 p.m. (range; 22:00-23:50 p.m.) and the average wake-up time from 11:30 a.m. (range; 9:20 a.m.-2:30 p.m.) to 7:50 a.m. (range; 7:20-8:30 a.m.). All patients have maintained the readjusted bedtime and wake-up time schedules for 3.8±2.4 months without additional light therapy. No adverse events of LT were observed.
Conclusion : A short-term LT was able to advance a delayed sleep phase and the advancement of sleep phase has been maintained for more than 3 months.
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Keywords:
Light therapy | Delayed sleep phase syndrome | Circadian rhythm sleep disorder |
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