| 폐쇄성 수면 무호흡증에서 활동기록기의 주기성 사지운동 진단에 관한 타당도 검증 |
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윤영훈, 김민주, 이민환, 김천식, 정유삼, 김우성, 이상암 |
1울산대학교 의과대학 서울아산병원 신경과학교실
2울산대학교 의과대학 서울아산병원 이비인후과학교실
3울산대학교 의과대학 서울아산병원 호흡기내과학교실 |
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| The Validation of Actigraphy for Detection of Periodic Leg Movement in Obstructive Sleep Apnea |
| Young Hun Yun, Min Ju Kim, Min Hwan Lee, Cheon Sik Kim, Yoo Sam Chung, Woo Sung Kim, Sang-Ahm Lee |
1Departments of Neurology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
2Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
3Pulmonary and Critical Medicinec, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea |
| Corresponding Author:
Sang-Ahm Lee ,Tel: +82-2-3010-3445, Fax: +82-2-474-4691, Email: salee@amc.seoul.kr |
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Received: September 13, 2010 Accepted: November 26, 2010 Published online: December 31, 2010 |
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| ABSTRACT |
Objectives: Several validation studies of actigraphy for periodic limb movements (PLMs) detection reported a high sensitivity and specificity in restless leg syndrome and periodic limb movement disorder. But PLMs also arise in association with a variety of other sleep disorders such as the sleep apnea syndrome. We compared PLM counts obtained with polysomnography (PSG) to those obtained from actigraphy with PAM-RL and assess the validity in patients with obstructive sleep apnea.
Methods: Sixty patients with obstructive sleep apnea underwent actigraphy from both legs and simultaneous PSG during awakeness and sleep. Each of left and right PLM indices by unilateral actigraphy were calculated automatically and compared to PLM index by PSG of ipsilateral leg. Additionally, a comparison among the severity of apnea-hypopnea index (AHI) in obstructive sleep disorder was performed.
Results: PLM index obtained with actigraphy were not different from PLM index by PSG [7.93(±11.65)/h vs. 6.50(±12.45)/h; p=0.257]. The sensitivity and specificity of actigraphy identifying patients with PLM index ≥15/h against respective PLM index determined by PSG were calculated (sensitivity/specificity: 0.53/0.88). The actigraphy didn’t overestimate PLM in overall OSA, but overestimate only in severe OSA.
Conclusions: This discrepancy between PSG and actigraphy in patient with OSA may be due to overestimate of actigraphy in severe OSA and to underestimate of PLM as PLM index increases. Actigraphy can’t replace PSG in the diagnostic assessment of PLM using cut-off values in patients with obstructive sleep apnea on account of this problem. |
| Keywords:
Actigraphy | Obstructive sleep apnea | Periodic limb movement | Polysomnography. |
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