| Home | E-Submission | Sitemap | Contact Us |  
J Korean Sleep Res Soc > Volume 6(1); 2009 > Article
J Korean Sleep Res Soc. 2009;6(1):24-28.         doi: https://doi.org/10.13078/jksrs.09006
렘수면행동장애의 치료
문혜진, 남현우
서울대학교 보라매병원 신경과
Treatment of REM Sleep Behavior Disorder
Hye-Jin Moon, Hyunwoo Nam
Department of Neurology, Boramae Hospital, Seoul National University, Seoul, Korea
Corresponding Author: Hyunwoo Nam ,Tel: +82-2-870-2471, Fax: +82-2-870-3866, Email: hwnam@brm.co.kr
Received: June 4, 2009   Accepted: June 20, 2009   Published online: June 30, 2009
Share :  
REM sleep behavior disorder (RBD) is clinically characterized by the intermittent loss of normal skeletal muscle atonia during rapid eye movement (REM) sleep with the appearance of elaborate motor activity associated with dream mentation. Clonazepam, a sedating benzodiazepine, is currently regarded as the treatment of choice for RBD. In patients with contraindications to clonazepam, in those unresponsive to clonazepam, or in whom tolerance or serious side effects are observed, a therapeutic trial with melatonin up to 12 mg is recommended. The effect of acetylcholinesterase inhibitors and dopaminergics on RBD symptoms needs future validation. There is no clear evidence of beneficial effect of bilateral subthalamic nucleus stimulation despite the improvement of the sleep architecture.
Keywords: REM sleep behavior disorder | Clonazepam | Melatonin | Pramipexole | Levodopa
Editorial Office
Joong-Ang Bldg., 18-8, Wonhyo-ro 89 Gil, Yonsan-gu, Seoul 04314, Republic of Korea
Tel: +82-2-717-5114   Fax: +82-2-717-5515   E-mail: jsleepmed@e-jsm.org

Copyright© Korean Sleep Research Society.                Developed in M2PI
About |  Browse Articles |  Current Issue |  For Authors and Reviewers