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J Korean Sleep Res Soc > Volume 5(2); 2013 > Article
J Korean Sleep Res Soc. 2013;5(2):64-69.         doi: https://doi.org/10.13078/jksrs.08011
지속적 양압기의 실제 임상 사용
성균관대학교 의과대학 삼성서울병원 신경과 수면센터
Positive Pressure Therapy; When CPAP fails, what other PAP modalities are?
Eun Yeon Joo
Department of Neurology, Sleep Center, Samsung Medical Center, Sungkyunkwan University School of Medicine,
Corresponding Author: Eun Yeon Joo ,Tel: +82-2-3410-3597, Fax: +82-2-3410-0052, Email: ejoo@skku.edu
Received: December 11, 2008   Accepted: December 20, 2008   Published online: December 31, 2008
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Positive airway pressure (PAP) is the treatment of choice for patients with moderate-to-severe obstructive sleep apnea (OSA). PAP can effectively reduce the apnea-hypopnea index and improve subjective and objective sleepiness. Also it can gives benefits in sleep quality and quality of life for both the patient and bed partner. Since continuous PAP (CPAP) treatment of OSA was described, additional modes of pressure delivery have been developed (bilevel PAP, autoadjusting PAP, flexible PAP). While none of the variants of PAP improves adherence in unselected patients compared to CPAP, individual patients may respond to a change in pressure mode. Although attended PAP titration remains the standard of practice for selecting a treatment pressure, use of autotitrating PAP devices in the unattended setting can provide an effective titration alternative with careful patient selection and review of titration results. However, despite the increase in PAP treatment options, lack of acceptance and inadequate adherence to PAP therapy remain the major causes of treatment failure. Heated humidification can improve PAP adherence, especially in patients with nasal congestion or dryness.
Keywords: Positive airway pressure (PAP) | Obstructive sleep apnea (OSA) | Continuous PAP (CPAP) | Bilevel PAP | Autoadjusting PAP | Flexible PAP
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Positive Airway Pressure Therapy of Obstructive Sleep Apnea  2006 June;3(1)
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