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REVIEW ARTICLE
J Korean Sleep Res Soc. 2008;5(1):33-38.         doi: https://doi.org/10.13078/jksrs.08005
Recent Update of Restless Legs Syndrome
Kwang Ki Kim
Department of Neurology, Dongguk University International Hospital
Corresponding Author: Kwang Ki Kim ,Tel: +82-31-961-7215, Fax: +82-31-961-7977, Email: neukim@duih.org
Received: 21 June 2008;  Accepted: 25 June 2008.
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ABSTRACT
Restless legs syndrome (RLS) is a very frequent neurological disorder characterised by sensory and motor symptoms. The diagnosis of RLS basically relies on the presence of 4 clinical criteria defined by the International RLS Study Group. So RLS is can be composed of various pathogenetic mechanisms. This review focuses on the recent developments in pathophysiology of RLS, with particular emphasis on the background of recent developments in genetics, neuroimaging, and animal studies. Neuroanatomical, neurophysiological, neuropharmacological, and neurogenetic findings have to be merged to reveal the secrets of restless legs syndrome.
Keywords: Restless legs syndrome | Pathophysiology
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