| 폐쇄성 수면 무호흡증후군을 동반한 말단비대증 |
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이정, 하충건, 윤창호 |
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인하대학교 의과대학 신경과학교실 |
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| Obstructive Sleep Apnea Syndrome Associated with Acromegaly |
| Jeong Lee, Choong-Kun Ha, Chang-Ho Yun |
| Department of Neurology, College of Medicine, Inha University. Incheon |
| Corresponding Author:
Chang-Ho Yun ,Tel: +82-32-890-3418, 386, Fax: +82-32-890-3864, Email: ych333@inha.ac.kr |
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Received: December 4, 2006 Accepted: December 24, 2006 Published online: December 31, 2006 |
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| ABSTRACT |
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Acromegaly can cause obstructive sleep apnea syndrome because excessive growth hormone (GH) results in abnormal growth of craniofacial skeleton and parapharyngeal soft tissue. A 46-year-old female patient presented with excessive daytime sleepiness and habitual snoring. Polysomnography and multiple sleep latency test documented moderate to severe degree of obstructive sleep-disordered breathings
and excessive daytime sleepiness. Craniofacial characteristics leaded to the endocrinologic study that confirmed excessive GH secretion. Sella magnetic resonance image revealed underlying pituitary macroadenoma. Craniofacial features should be carefully evaluated to find the underlying cause of obstructive sleep apnea. |
| Keywords:
Acromegaly | Obstructive sleep apnea syndrome | Pituitary macroadenoma |
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