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J Korean Sleep Res Soc > Volume 3(2); 2006 > Article
J Korean Sleep Res Soc. 2006;3(2):102-106.         doi: https://doi.org/10.13078/jksrs.06018
폐쇄성 수면 무호흡증후군을 동반한 말단비대증
이정, 하충건, 윤창호
인하대학교 의과대학 신경과학교실
Obstructive Sleep Apnea Syndrome Associated with Acromegaly
Jeong Lee, Choong-Kun Ha, Chang-Ho Yun
Department of Neurology, College of Medicine, Inha University. Incheon
Corresponding Author: Chang-Ho Yun ,Tel: +82-32-890-3418, 386, Fax: +82-32-890-3864, Email: ych333@inha.ac.kr
Received: December 4, 2006   Accepted: December 24, 2006   Published online: December 31, 2006
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Acromegaly can cause obstructive sleep apnea syndrome because excessive growth hormone (GH) results in abnormal growth of craniofacial skeleton and parapharyngeal soft tissue. A 46-year-old female patient presented with excessive daytime sleepiness and habitual snoring. Polysomnography and multiple sleep latency test documented moderate to severe degree of obstructive sleep-disordered breathings and excessive daytime sleepiness. Craniofacial characteristics leaded to the endocrinologic study that confirmed excessive GH secretion. Sella magnetic resonance image revealed underlying pituitary macroadenoma. Craniofacial features should be carefully evaluated to find the underlying cause of obstructive sleep apnea.
Keywords: Acromegaly | Obstructive sleep apnea syndrome | Pituitary macroadenoma
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