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J Korean Sleep Res Soc > Volume 2(2); 2005 > Article
J Korean Sleep Res Soc. 2005;2(2):41-43.         doi: https://doi.org/10.13078/jksrs.05015
일시적으로 간뇌의 뇌혈류 감소를 보이는 클레인-레빈 증후군 1예
주은연, 태우석, 한선정, 김선화, 이성익, 홍승봉
1성균관의대 삼성서울병원 신경과
2원광대 산본병원 신경과
Episodic diencephalic hypoperfusion in Kleine-Levin syndrome
Eun Yeon Joo, Woo Suk Tae, Sun Jung Han, Sun Wha Kim, Sung-Ik Lee, Seung Bong Hong
1Department of Neurology, Samsung Medical Center and Center for Clinical Medicine, SBRI, Sungkyunkwan University School of Medicine, Seoul
2Department of Neurology, San-bon Won Kwang University hospital, Kumpo, Korea
Corresponding Author: Seung Bong Hong ,Tel: +82-2-3410-3592, Fax: +82-2-3410-0052, Email: sbhong@smc.samsung.co.kr
Received: November 16, 2005   Accepted: December 23, 2005   Published online: December 31, 2005
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We report a 24 year-old woman presenting with recurrent episodes of hypersomnia, apathy, personality changes, irritability and hyperphagia since February 2001. Brain single photon emission computed tomography (SPECT) was performed during symptomatic and asymptomatic periods, respectively and then subtracted ictal SPECT coregistered to MRI (SISCOM) was done between those two SPECT images. Interictal brain SPECT suggested suspicious hypoperfusion in right mesial temporal region whereas ictal SPECT showed hypoperfusion in bilateral frontal and temporal lobes, and thalami/hypothalami. SISCOM showed significantly decreased perfusion in thalamus/hypothalamus and frontotemporal regions during a symptomatic period.
Keywords: Kleine-Levin syndrome | SPECT | Thalamus | Hypothalamus | Hypersomniar
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A Case of Atypical Kleine-Levin Syndrome  2013 December;10(2)
Typical Kleine-Levin syndrome  2006 June;3(1)
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