| Home | E-Submission | Sitemap | Contact Us |  
REVIEW ARTICLE
J Korean Sleep Res Soc. 2010;7(2):25-31.         doi: https://doi.org/10.13078/jksrs.10005
The Efficacy and Safety of Long-Term Use of Hypnotics
Kwang Ik Yang, and Young Hwangbo
1Department of Neurology, College of Medicine, Soonchunyhang University, Cheonan Hospital, Cheonan, Korea
2Department of Preventive Medicine, College of Medicine, Soonchunyhang University, Cheonan, Korea
Corresponding Author: Kwang Ik Yang ,Tel: +82-41-570-2290, Fax: +82-41-579-9021, Email: kiyang@sch.ac.kr
Received: 30 November 2010;  Accepted: 13 December 2011.
Share :  
ABSTRACT
Insomnia may present with a variety of complaint and etiology, making the evaluation and management of chronic insomnia demanding on a clinician’s time. Long-term use of hypnotics and sedatives has been discouraged for a number of reasons, including tolerance, abuse liability, and the belief that insomnia is a symptom that remit with treatment of the underlying medical or psychiatric disorder. Moreover, pharmacotherapy produces only moderate improvement during drug administration and returns toward baseline after discontinuation. Although efficacy and safety have been established for benzodiazepine receptor agonists when used for short-duration therapy, there are few data that establish their continued efficacy and safety in long-term use. Benzodiazepine hypnotics have been implicated as a cause of numerous adverse events, including dependency, withdrawal, rebound symptom, daytime sedation, fall, and hip fracture, especially in older people. In order to use hypnotic properly, correct diagnosis of the underlying causes of sleep disturbance is acquired at first and extreme caution of hypnotics use to primary sleep disorders is needed, especially in sleep related breathing disorders. Physicians and patients should be cautioned about the potential adverse effects and using of hy-pnotics. After initial treatment, clinical efficacy and side effect should be observed regularly. Easy accessibility of cognitive behavior therapy for patient can be also a coping with long-term use of hypnotics. J Korean Sleep Res Soc 2010;7:25-31
Keywords: Insomnia | Hypnotics | Safety
TOOLS
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
  E-Mail
Share:      
METRICS
2
Crossref
982
View
8
Download
Editorial Office
Department of Neurology, Kyungpook National University Chilgok Hospital
807, Hoguk-ro, Buk-gu, Daegu 41404, Republic of Korea
Tel: +82-53-200-2582   Fax: +82-53-200-3299   E-mail: jsleepmed@gmail.com

Copyright© Korean Sleep Research Society. All rights reserved.               powerd by M2community
About |  Browse Articles |  Current Issue |  For Authors and Reviewers