Central Sleep Apnea in Heart Failure: Clinical Implications,Recognition, and Management |
윤창호 |
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Central Sleep Apnea in Heart Failure: Clinical Implications,Recognition, and Management |
Chang-Ho Yun |
Department of Neurology, College of Medicine, Inha University, Incheon, Korea |
Corresponding Author:
Chang-Ho Yun ,Tel: +82-32-890-3418, 386, Fax: +82-32-890-3864, Email: ych333@chol.com/ych333@inha.ac.kr |
Received: June 11, 2008 Accepted: June 25, 2008 Published online: June 30, 2008 |
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ABSTRACT |
Central sleep apnea (CSA) is characterized by a lack of respiratory drive during sleep, resulting in repetitive periods of insufficient
ventilation and compromised gas exchange. These nighttime breathing disturbances can lead to daytime impairment and poor cardiovascular
outcomes. There are several types of CSA, including idiopathic CSA, high altitude-induced periodic breathing, obesity
hypoventilation syndrome, drug-induced central apnea, and Cheyne-Stokes breathing pattern. While unstable ventilatory control during
sleep is the hallmark of CSA, the pathophysiology and the prevalence of the various forms of CSA varies greatly. Among them, CSA
associated with heart failure is well-studied in the respect of clinical impact and management strategy. Through this article, I will summarize
the underlying pathophysiology, clinical impacts, and potential treatment of CSA occurring in subjects with heart failure.
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Keywords:
Sleep disorderd breathing | Pathophysiology | Cheyne-Stokes respiration | Continuous positive airway pressure |
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